Brody had very high fevers most the night. He felt okay despite this. He was just mostly tired. He has been sleeping, sleeping, and sleeping. This morning his fever is much lower (low grade fever). He is still sleeping right now. His kidney function labs have shown that his kidney function has gotten significatly worse since yesterday. And, we just found out this morning that his nephrostomy tube cultures are growing E. Coli. Infectious disease doc has been consulted to determine most appropriate antibiotics to treat E. Coli in a kidney with acute renal failure. I was just told they have decided to go with Zosyn and Linezolid.
It's most likely that Brody's kidney was introduced to the E. Coli infection during last weeks surgery. When Brody came in yesterday morning to have the surgery, he was not acting like himself. He did not yet have a fever but he was unusually tired (excessively tired and weak acting). His white counts were high too. (The elevated white counts is what prompted the oncologist to collect samples for culture after Brody's surgery yesterday). His surgery yesterday was to place an internal stent from his kidney to his bladder. He already had an external nephrostomy tube (a tube that runs from his kidney, through his back and empties into a bag). Brody has had both of these before. He prefers the internal version rather than external. The external one was placed last week on Thursday. The eventual hope was to be able to remove the external tube and Brody would only have the internal one. Right now he has both. Anyhow, based on how Brody was feeling before surgery, his white counts being elevated before the surgery and then immediately after surgery feeling bad and that his nephrostomy tube culture is growing E. Coli, it's most likely that he developed the infection last week during the surgery to place the nephrostomy tube. Bill and I have not yet had to do any dressing changes nor flushes of the tube since it was placed. The potential opportunity that we could have introduced this infection does not exist. It most likely occured during the surgery last week. However, I am wondering if the E. Coli might be a contaminate. It's possible the culture could have been contaminated. The opening for the drain of the nephrostomy tube could have been contaminated with E. Coli and then the urine flowed through this into the collection cup. You cannot completely disinfect the drain opening/closure without dipping it in a cup of disinfectant. The nurse who collected the sample to be used for culture did not do this. She cleaned it with betadine using a swab all around the outside where hands etc would have to touch the opening/closure valve. There are parts where you have to open the tube to drain it that cannot be cleaned with a swab. The sample from the tube was taken right after his surgery yesterday. The nephrostomy tube he had last week was removed during yesterday's procedure and a new external one was placed as they were placing the internal one. So since this one was so new when the sample was drawn there was not much opportunity for E. Coli to have contaminated the part of the tube opening that cannot be disinfected with just a swab. If E. Coli is the culprit agent and Brody's kidney is infected with it, this infection was most likely introduced during his surgery last week.
Please pray, cross fingers, make a wish etc for Brody to have complete recovery from all of this.
Prayers for you and your family.
ReplyDeleteLove,
Teri & Don Moss